{"title":"Forensic Genomic Innovations Hub","description":null,"products":[{"product_id":"alex3","title":"ALEX³ Comprehensive IgE Allergy Test - NEW","description":"\u003cp dir=\"auto\"\u003eForensic Genomics Innovation Hub (FGIH) has provided clinically oriented diagnostic testing from its UK laboratory, supporting both healthcare practitioners and individuals seeking high-resolution insights into immune responses. Best known for its work in forensic genomics and functional health testing, the laboratory offers the \u003cstrong\u003eAllergy Solution – ALEX³ Comprehensive IgE Allergy Test\u003c\/strong\u003e, t\u003cmeta charset=\"utf-8\"\u003ehe new-generation upgrade of the earlier ALEX² assay.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eIt measures specific IgE against a broad panel of allergen extracts and molecular components. This allows clinicians to see how the immune system is actually responding to individual proteins, not only which allergen sources are present.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eWhat it Covers and why it's clinically relevant\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eNormal immune tolerance keeps the body from mounting an IgE response to harmless substances such as pollens, foods, animal dander, mites, moulds, and insect venoms. When this tolerance breaks down, IgE antibodies form and can trigger symptoms ranging from rhinitis and eczema to gastrointestinal reactions or anaphylaxis. Problems can appear at any age and are influenced by genetics, environmental exposure, barrier function, and co-factors. Traditional extract-based testing shows sensitisation to whole allergen sources (for example, apple or birch pollen). The ALEX³ panel goes further by also measuring molecular allergens—specific protein components within those sources so cross-reactions (such as pollen–food syndromes) and heat-stable versus heat-labile allergens can be identified. This phenotypic information is useful both at baseline and for guiding and monitoring dietary, environmental, or immunotherapy strategies.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eThe panel reports specific IgE levels for 300 allergens (82 allergen extracts and 218 molecular allergens), covering 80 allergen families and 145 allergen sources, plus a semi-quantitative total IgE result. Molecular allergens help distinguish true primary sensitisation from cross-reactivity, assess the risk of systemic versus mild reactions, and indicate whether cooking or processing may reduce allergenicity. Non-specific IgE directed against cross-reactive carbohydrate determinants (CCDs) is blocked during the assay, improving specificity and reducing false-positive results. Unlike some allergy tests, the assay does not require patients to stop antihistamines or other symptom-relief medications.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eClinically, the profile is used when IgE-mediated allergy or complex sensitisation patterns are in question—respiratory symptoms, food reactions, oral allergy syndrome, eczema, insect-venom risk assessment, latex allergy, and work-ups for immunotherapy candidacy. Results can direct targeted avoidance, guide safe reintroduction of cooked versus raw foods, support referral decisions, and help avoid unnecessarily restrictive diets by clarifying which components are clinically relevant.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e \u003c\/p\u003e\n\u003chr\u003e\n\u003ch3 dir=\"auto\"\u003eTest specifications\u003c\/h3\u003e\n\u003cp dir=\"auto\"\u003eAllergy Solution – ALEX³ Comprehensive IgE Allergy Test\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eSample type:\u003c\/strong\u003e Blood Drae or Capillary blood (finger-prick) c\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eKey markers:\u003c\/strong\u003e Specific IgE to 300 allergens (218 molecular allergens + 82 allergen extracts); semi-quantitative total IgE; coverage of major food, pollen, mite, mould, animal, insect-venom, and latex sources with component-resolved detail.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eTurnaround Time: \u003c\/strong\u003e5 days\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cbr\u003e\u003cstrong\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0578\/1287\/7465\/files\/Sample_Report_Methylation_1.pdf?v=1788844656\" title=\"Doctors Data Methylation Profile Plasma\"\u003e\u003c\/a\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0578\/1287\/7465\/files\/ALEX3_FGIH_Demo_Report.pdf?v=1791953953\" title=\"Alex3 Sample Report\"\u003eSample Report \u003c\/a\u003e\u003c\/strong\u003e\u003c\/p\u003e","brand":"Forensic Genomic Innovations Hub","offers":[{"title":"Default Title","offer_id":67700393672857,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/1287\/7465\/files\/Screenshot2026-10-14at12.39.13PM.png?v=1791952762"},{"product_id":"pharmacogenetics","title":"PgX Pharmacogenomics Test","description":"\u003cp dir=\"auto\"\u003eForensic Genomics Innovation Hub (FGIH) provides clinically oriented DNA testing from its UK laboratory, supporting healthcare practitioners and individuals with actionable genetic insights. The Pharmacogenomics Test is a comprehensive panel that examines variations in 39 genes involved in drug metabolism and response. It shows how an individual’s DNA influences the way prescribed and over-the-counter medications are processed, so dosing and selection can be guided by actual metabolic capacity rather than by trial and error alone.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eNormal drug metabolism depends on enzymes (particularly the cytochrome P450 family and other transporters and targets) that convert medications into active or inactive forms, control their clearance, and influence how they reach their sites of action. Variations in the genes that code for these enzymes produce different metaboliser phenotypes—poor, intermediate, normal, rapid, or ultra-rapid. A poor metaboliser may accumulate a drug and experience side-effects or toxicity at standard doses; an ultra-rapid metaboliser may clear it so quickly that the same dose is ineffective. These differences cannot be predicted from age, sex, or clinical history alone. The test reports only genes and variants with documented clinical guidance, translating genotype into practical recommendations for medication choice and dose adjustment.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cbr\u003e\u003cstrong\u003eWhat it Covers and why it's clinically relevant\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eThe panel covers 39 genes that affect response to many commonly used medications across cardiovascular and stroke prevention (including clopidogrel), mental health, neurological and pain conditions, oral contraceptives, hormone replacement therapy, and other therapeutic areas. The medication list expands as new evidence is published. Results are interpreted using tools such as ReviewGx and TreatGx, which can incorporate additional clinical data (current and past medications, organ function, allergies, and comorbidities). Because DNA does not change, the test is performed once and can be re-reviewed later when new medications are considered.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003eClinically, the profile is used when medication response, side-effects, or treatment failure is in question—patients taking multiple drugs, those with cardiovascular risk on antiplatelet therapy, individuals prescribed antidepressants or antipsychotics, people starting hormone therapy, and anyone seeking to reduce the risk of adverse reactions or ineffective treatment. It helps direct selection of alternative agents or adjusted doses and supports safer, more effective prescribing while acknowledging that non-genetic factors (drug–drug interactions, age, weight, liver or kidney function) also influence outcomes.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003chr\u003e\n\u003ch3 dir=\"auto\"\u003eTest specifications\u003c\/h3\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eSample type:\u003c\/strong\u003e \u003cmeta charset=\"utf-8\"\u003eBuccal swab (epithelial cells from the inside of the mouth).\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eKey markers: \u003c\/strong\u003eVariants in 39 genes responsible for drug metabolism and response; clinically actionable recommendations for commonly used medications across cardiovascular, mental health, neurological, pain, contraceptive, and hormone-therapy categories.\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cstrong\u003eTurnaround Time: \u003c\/strong\u003e20 days\u003c\/p\u003e\n\u003cp dir=\"auto\"\u003e\u003cbr\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0578\/1287\/7465\/files\/Long-Demo-FGIH-Demo1_FGIH.pdf?v=1791953957\" title=\"Pharmacogenetics Report\"\u003e\u003cstrong\u003eSample Report \u003c\/strong\u003e\u003c\/a\u003e\u003c\/p\u003e","brand":"Forensic Genomic Innovations Hub","offers":[{"title":"Default Title","offer_id":67700413104281,"sku":null,"price":0.0,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/1287\/7465\/files\/Screenshot2026-10-14at12.49.27PM.png?v=1791953375"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0578\/1287\/7465\/collections\/Screenshot_2026-10-14_at_12.52.44_PM.png?v=1791953732","url":"https:\/\/www.lablink.asia\/en-th\/collections\/forensic-genomic-innovations-hub.oembed","provider":"Lab Link","version":"1.0","type":"link"}