TruAge by TruDiagnostics

Biological Age Score: OMICmAge (Multi-Omic Methylation Age)

The OMICmAge is a state-of-the-art epigenetic clock trained on over 1.1 million CpG sites across the genome, integrating DNA methylation with multi-omic data layers (transcriptomics, proteomics, and clinical biomarkers) for superior accuracy.

• Algorithm: Trained on 13,661 diverse samples with causal and predictive machine learning models
• Correlation with chronological age: r = 0.97 (outperforms Horvath, Hannum, PhenoAge, and GrimAge)
• Mean Absolute Error (MAE): 2.7 years – the lowest error rate among commercial epigenetic clocks
• Biological relevance: Captures mitochondrial function, inflammation, immune senescence, and metabolic efficiency

Clinical Applications:

• Identify patients ageing faster than chronological age (high OMICmAge delta)
• Track reversal potential – average 1.5–3 year reduction in OMICmAge after 6 months of optimised protocols
• Benchmark against population norms (50th, 75th, 90th percentiles provided)

“OMICmAge is the first clock to integrate causal omics data, making it uniquely responsive to interventions.”
Dr. Kara Fitzgerald, Epigenetics Researcher

Grip Strength & Gait Speed (Functional Age Markers)

• Predicted from epigenetic data (no equipment needed)
• Validated against NIH Toolbox norms
• Flags sarcopenia risk 5–10 years early

DunedinPACE – Pace of Aging

• Measures rate of aging (not just state)
• 1.0 = average (1 year older per chronological year)
• <0.8 = slow ager (elite responders)
• 1.2 = fast ager (high intervention priority)

Smoking & Alcohol Impact Scores

• Quantifies epigenetic damage in pack-years and drink-years
• Shows residual damage even after cessation
• Motivational tool for behavior change

Telomere Length Report

• Percentile ranking vs. age-matched peers
• Tracks telomere attrition/re-elongation over time
• Correlates with OMICmAge for cross-validation

Unlock Deeper Insights with the TruHealth + TruAge Combo Combine TruAge (epigenetic age, immune clocks, inflammation, organ aging) with TruHealth (hs-CRP, HbA1c, HOMA-IR, Omega-3 Index, Vitamin D, RBC Mg, Glutathione, Cortisol:DHEA, ApoB, Lp(a), Glyphosate, Mercury). See why biological age improves — link epigenetic reversal to real-time nutrient, metabolic, and toxin shifts.

Key Markers: OMICmAge, 11 Organ-System Ages, 2-Cell Immunity (CD4+, CD8+), Inflammation (CRP, IL-6), Grip Strength, Gait Speed, DunedinPACE, Smoking Impact, Alcohol Impact, Telomere Length

Sample Type: Blood Spot

Turnaround Time: 4 weeks 

Sample Report